SERENIN Max

Serenin Max combines natural ingredients that work together to promote normal behavioral patterns and a healthy nervous system, particularly in times of stress.

$50.00

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60 Capsules per Bottle

Product Code: NN121

Price for US Customers Only

Serenin Max provides natural ingredients to promote normal, calm behavioral patterns, particularly during times of stress, and to maintain a healthy nervous system and brain function supporting healthy cognition. These ingredients work together to achieve this calming effect and include:

St. John’s Wort extract, with active constituents hyperforin and hypericin, promotes healthy mentation and behavioral patterns by modulating serotonin, dopamine, and norepinephrine; reducing serotonin reuptake in the brain; and inhibiting GABA ligand binding.¹
Eleuthero powder, an adaptogen, aids in the body’s ability to cope with environmental stress and anxiety by modulating the nitric oxide and cortisol production via the hypothalamic-pituitary axis.²
Passion flower extract, containing flavonoids and alkaloids, promote relaxation by inhibiting GABA uptake by nerve cell synapses.³
DL-phenylalanine is a form of an essential amino acid that promotes normal mood and behavior via two mechanisms. First, phenylalanine is a precursor for norepinephrine production and helps to maintain healthy amounts of the neurotransmitter. Second, phenylalanine is metabolized to the neuromodulator 2-phenylethylamine. An increase in the production of this metabolite helps to maintain normal mood and attention either by greater available concentration or by improvement of brain neuron receptor sensitivity.⁴
NOTE: If pregnant or lactating, please discuss with your doctor before use.
5-HTP (Griffonia simplicifolia seed), a metabolite produced from essential amino acid L-tryptophan and a direct precursor for serotonin production in the CNS that promotes serotonin production and thereby healthy behavioral responses in times of stress.⁵

References:

¹ Butterweck V, Wall A, Lieflander-Wulf U, Winterhoff H, and Nahrstedt A. Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity. Pharmacopsychiatry. 1997; 30(Suppl 2): 117-124.

² Wilson L. Review of adaptogenic mechanisms: Eleuthrococcus senticosus, Panax ginseng, Rhodiola rosea, Schisandra chinensis, and Withania somnifera. Australian Journal of Medical Herbalism. 2007; 19(3): 126-131.

³ Appel K, Rose T, Fiebich B, Kammler T, Hoffman C, and Weiss G. Modulation of the γ-aminobutyric acid (GABA) system by Passifora incarnata L. Phytother Res. 2011; 25(6): 838-843.

⁴ Kravitz HM, Sabelli HC, and Fawcett J. Dietary supplements of phenylalanine and other amino acid precursors of brain neuroamines in the treatment of depressive disorders. J Am Osteopath Assoc. 1984; 84(1 Suppl): 119-123.

⁵ Birdsall TC. 5-Hydroxytryptophan: A clinically effective serotonin precursor. Altern Med Rev. 1998; 3: 271-280.

	Daily Use
Children Under 16	Contact Natural Necessity
Adult Daily Use	Take two (2) capsules as a dietary supplement, or as directed by a qualified health care professional. Uso Sugerido: Tomar dos (2) capsulas diarias como suplemento nutricional o segun indicacion medical.

Serving Size: 1 Capsules

Capsules Per Bottle: 60

Ingredient	Amount per Serving
Vitamin B-6 (as pyridoxine HCl)	25 mg
Folate (as folic acid)	400 mcg
Vitamin B-12 (as cyanocobalamin)	200 mcg
Magnesium (as magnesium oxide)	100 mg
Selenium (as selenium amino acid chelate)	70 mcg
5-HTP (L-5-hydroxy-tryptophan (Griffonia simplicifolia) (seed)	25 mg
DL- Phenylananine	40 mg
Eleuthero powder (Eleutherococcus senticosus)(rhizome)	70 mg
Inositol	100 mg
L-Tyrosine	10 mg
St. John's Wort extract (Hypericum perforatum)(flower heads)(std. for 0.3% Hypericin (1.8 mg))	600 mg
Passion Flower extract (Passiflora incarnata) (aerial parts)(std. for >3.5% flavonoids as Isovetexin (1.75 mg))	50 mg